I-Tribedoce iquka ivithamini B1 (thiamine hydrochloride) , ivithamini B12 (hydroxocobalamin) , ivithamini B6 (pyridoxine hydrochloride) . Inefuthe eliluncedo ekusebenzeni kwesibindi kunye nakwinkqubo yemithambo-luvo. Ukwenza ukuba igazi lijiye kwiidosi eziphezulu kubangela ukwanda kwethromboplastin kunye nomsebenzi weprothrombin.
Isenzo amayeza
Tribedoce) ibhekisa kwiqela leevithamini ezinyibilikayo emanzini. Inomsebenzi ophezulu webhayoloji. I-Tribedoce (i-vitamin B12 (i-hydroxocobalamin)) iyadingeka kwi-hematopoiesis yesiqhelo (ikhuthaza ukuvuthwa kweeseli ezibomvu zegazi).
Ithatha inxaxheba kwiinkqubo zokudlulisa, ukuthuthwa kwe-hydrogen, ukuhlanganiswa kwe-methionine, i-nucleic acids, i-choline, i-creatine. Inegalelo ekuqokeleleni ii-erythrocytes zeekhompawundi eziqukethe amaqela e-sulfhydryl.
Pharmacokinetics
Emva kokulawulwa ngomlomo, i-Tribedoce (i-vitamin B12 (i-hydroxocobalamin)) ifunxwe kwiphecana lesisu. I-Metabolized in tissue, eba luhlobo lwe-coenzyme-adenosylcobalamin, eyindlela esebenzayo ye-cyanocobalamin. Ikhutshwe kwi-bile kunye nomchamo.
Kutheni le nto iTribedoce) imiselwe?
I-anemia ngenxa ye-B12 yokuswela kweemeko; kunyango olunzima lwentsimbi kunye ne-post-hemorrhagic anemia; i-aplastic anemia ebangelwa zizinto ezinetyhefu kunye neziyobisi; isifo sesibindi (hepatitis, cirrhosis); i-myelosis ehlekisayo; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; usana lobuchopho bokukhubazeka, i-Down syndrome, ukwenzakala kwemithambo-luvo; izifo zolusu (i-psoriasis, i-photodermatosis, i-dermatitis herpetiformis, i-neurodermatitis); Ukuthintela nokunyanga iimpawu ze-Tribedoce (vitamin B12 (hydroxocobalamin)) ukusilela (kubandakanya ukusetyenziswa kwe-biguanide, i-PASA, i-vitamin C ngeedosi eziphezulu); ukugula kwemitha
Isisombululo kunye nolawulo
Tribedoce) isetyenziswa njenge-SC, IV, IM, intralumbar kunye nenaliti yenaliti. Nge-anemia ehambelana nokusilela kwe-Tribedoce (ivithamini B12 (i-hydroxocobalamin)) yaziswa kwi-100-200 mcg kwiintsuku ezi-2.
Kwigazi Iimpawu ze-myelosis ye-funicular kunye ne-megalocytic anemia enezifo ze inkqubo ye-nervous: I-400-500 micrograms kwiintsuku ezisi-7 zokuqala ngosuku, emva kwexesha eli-1 rhoqo kwiintsuku ezingama-5-7.
Ngexesha lokuxolelwa xa kungekho siganeko sokugcina idosi ye-myelosis ye-funicular - 100 mcg amaxesha ama-2 ngenyanga, phambi kweempawu zemithambo-luvo - ukuya kwi-200-400 mcg amaxesha ama-2 ngenyanga.
Kwi-post-hemorrhagic anemia kunye ne-iron anemia kwi-30-100 mcg amaxesha ama-2-3 ngeveki. Xa i-aplastic anemia (ngakumbi ebantwaneni) -i-100 micrograms ngaphambi kokuphuculwa kweklinikhi.
Xa i-anemia yesondlo kwiintsana kunye neentsana ezizelwe ngaphambi kwexesha-i-30 mcg / usuku kangangeentsuku ezili-15.
Kwizifo zenkqubo esembindini kunye neparipheral ye-nervous system kunye nezifo zemithambo-luvo ezinesifo sentlungu ilawulwa ngokwanda kweedosi - i-200-500 mcg, kunye nophuculo kurhulumente - i-100 mcg / usuku.
Inkqubo yokonyango kwi-Tribedoce (i-vitamin B12 (i-hydroxocobalamin) iiveki ezi-2. Kwizilonda ezothusayo zenkqubo yemithambo-luvo: kwi-200-400 mcg yonke eminye imihla kangangeentsuku ezingama-40-45.
Xa i-hepatitis kunye ne-cirrhosis: I-30-60 mcg / imini okanye i-100 mg yonke eminye imihla yeentsuku ezingama-25-40.
I-Dystrophy kubantwana abancinci, i-Down syndrome kunye ne-cerebral palsy: kwi-15-30 mcg yonke imihla.
Xa i-funicular myelosis, i-amyotrophic lateral sclerosis inokungeniswa kumjelo womqolo kwi-15-30 mcg, ngokuthe ngcembe inyusa idosi ye-200-250 micrograms.
Ekuguleni kwemitha, isifo seswekile, ukuphazamiseka kwi-60-100 mcg ngemini kangangeentsuku ezingama-20 ukuya kwezi-30.
Xa i-Tribedoce (Vitamin B12 (Hydroxocobalamin)) isilela ukunqanda-IV okanye i-IM kangange-1 mg 1 ixesha ngenyanga; Unyango: IV okanye i-IM ye-1 mg ngosuku ngeeveki eziyi-1-2, idosi yesondlo yi-1-2 mg IV okanye i-IM ye-1 ngeveki, ukuya kuthi ga kwi-1 ngenyanga. Ubude bonyango bumiselwe ngokukodwa.
Intengiso
Izizwe ezilishumi elinambini iziphumo ebezingalindelekanga, iimpendulo ezigwenxa
I-CNS: kunqabile, imeko yokonwaba.
Inkqubo yentliziyo: kunqabile - iintlungu entliziyweni, i-tachycardia.
Ukungaphenduli komzimba: kunqabile - urticaria.
Tribedoce) Izimo
I-Thromboembolism, erythremia, erythrocytosis, ukonyusa ubuntununtunu kwi-cyanocobalamin.
Tribedoce) ngexesha lokukhulelwa kunye nokuncancisa
I-cyanocobalamin ingasetyenziselwa ukukhulelwa ngokweendlela zokupheka.
Imiyalelo ekhethekileyo
Xa i-stenocardia kufuneka isetyenziswe ngononophelo kwidosi enye ye-Tribedoce) 100 mcg. Ngexesha lonyango umfanekiso wegazi kunye nokujiya kufuneka kuhlolwe rhoqo. Akwamkelekanga ukufaka isirinji efanayo kunye ne-thiamine kunye ne-pyridoxine cyanocobalamin solutions.
Intsapho intsebenziswano elinambini
Ukusetyenziswa kweTribedoce (Vitamin B12 (Hydroxocobalamin)) kunye nezicwangcisi zehomoni kulawulo lomlomo zinokunciphisa uxinzelelo lwecyanocobalamin kwiplasma.
Kwisicelo samayeza anticonvulsant, ukufunxwa kwe-cyanocobalamin ngamathumbu kuye kwancipha.
Ukusetyenziswa kweTribedoce (Vitamin B12 (Hydroxocobalamin)) neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, iziyobisi zepotassium zinciphise ukufakwa kwecyanocobalamin ngamathumbu.
I-cyanocobalamin inokunyusa ukungahambelani komzimba okubangelwa yi-thiamine.
Xa isicelo parenteral of chloramphenicol kunganciphisa iziphumo hematopoietic cyanocobalamin kunye anaemia.
Ukungangqinelani kwamayeza
Iqulathwe kwimolekyuli ye-cobalt ye-cyanocobalamin inegalelo ekutshatyalalisweni kwe-ascorbic acid, thiamine bromide, riboflavin kwisisombululo.
Intengiso
I-Tribedoce amayeza asebenzayo aqukethe igama lebrendi kunye neziyobisi eziqhelekileyo ezinxulumene:
Into esebenzayo yinxalenye yeyeza okanye ichiza elisebenza ngokwendalo. Eli candelo leziyobisi linoxanduva lwenyathelo eliphambili lesiyobisi esenzelwe ukunyanga okanye ukunciphisa uphawu okanye isifo. Ezinye iinxalenye zeziyobisi ezingasebenziyo zibizwa ngokuba zii-excipients; Indima yayo kukusebenza njengesithuthi okanye ibinder. Ngokungafaniyo nesithako esisebenzayo, indima yesithako esingasebenziyo ayibalulekanga ekunyangeni okanye ekunyangeni isifo. Kunokubakho enye okanye ezingaphezulu izithako ezisebenzayo kwiyeza.
- Vitamin B1 (thiamine hydrochloride)
- Vitamin B12 (hydroxocobalamin)
- Vitamin B6 (pyridoxine hydrochloride)
Iinkampani zoxubo-ntloko ezilishumi elinambini:
Iinkampani ezixuba amayeza ziinkampani ezenza amayeza ezinceda kuphuhliso lonke lweziyobisi, ukusuka kuphando lwangasemva ukuya kuqeqesho, uvavanyo lwezonyango, ukukhutshwa kweziyobisi kwintengiso, kunye nentengiso yeziyobisi.
Abaphandi ngabantu abajongene nophando lwesayensi kunye nazo zonke iimvavanyo zeklinikhi zangaphambili ezikhokelele kuphuhliso lwechiza.
Imibuzo esoloko ibuzwa
Ngaba ndingaqhuba okanye ndisebenzise oomatshini abasindayo emva kokuthatha iTribedoce?
Kuxhomekeke ekuphenduleni kweTribedoce emva kokuyithatha, ukuba uziva unesiyezi, ukozela okanye nayiphi na impendulo ebuthathaka emzimbeni wakho, ke cinga ukuba iTribedoce ayikhuselekanga ukuqhuba okanye ukusebenzisa oomatshini abanzima emva kokusetyenziswa.
Oko kuthetha ukuba musa ukuqhuba okanye ukusebenzisa oomatshini abasindayo emva kokuthatha iphilisi. Njengoko kuyalelwe ngusokhemesti, kuyingozi ukusela utywala ngelixa uthatha amayeza, njengoko kubhenca izigulana ukozela kunye nomngcipheko wezempilo.
Yazi lempembelelo, ngakumbi xa uthatha i-Primosa capsule. Kuyacetyiswa ukuba ubonane nogqirha wakho kwangethuba ukuze ufumane iingcebiso ezifanelekileyo kunye nothethwano lonyango. Ngaba i-Tribedoce iyakhobokisa okanye ngumkhwa owenza?
Amachiza awenzelwanga ngenjongo yokudala iziyobisi okanye ukusetyenziswa gwenxa kwempilo yabasebenzisi. Iyeza elikhoboka libizwa ngokuba zizinto ezilawulwa ngurhulumente. Umzekelo, iShedyuli H okanye i-X e-India kunye neShedyuli II-V e-United States zizinto ezilawulwayo.
Jonga incwadana yemiyalelo yeziyobisi ngendlela yokuyisebenzisa kwaye uqiniseke ukuba ayisiyonto ilawulwayo. Ukuqukumbela, ukuzinyanga ngokwakho kuyingozi kwimpilo yakho. Nxibelelana nogqirha wakho ukufumana amayeza afanelekileyo, ingcebiso kunye nezikhokelo.
Ukugqithisa
Ukuba umntu ugqithisile kwaye uneempawu ezinzima njengokuphelelwa ngamandla okanye ukuphefumla kancinci, tsalela umnxeba kwi-911. Ngaphandle koko, tsalela iziko lokulawula ityhefu kwangoko. Abahlali baseUnited States banokubiza iziko labo lokulawula ityhefu 1-800-222-1222 . Abahlali baseCanada banokubiza iziko lokulawula ityhefu kwiphondo. Iimpawu zokudlula ngaphezulu zinokubandakanya: ukuxhuzula.
Amanqaku
Musa ukwabelana nabanye ngeli yeza. Iilebhu kunye / okanye iimvavanyo zonyango (ezinjengokubala okupheleleyo kwegazi, uvavanyo lomsebenzi wezintso) kufuneka zenziwe ngelixa usebenzisa eli yeza. Gcina konke ukuqeshwa kwezonyango nakwilabhoratri.
Ukugcina
Qhagamshelana nemiyalelo yemveliso kunye nekhemesti yakho ngeenkcukacha zokugcina. Gcina onke amayeza kwindawo engenakufikelelwa ngabantwana nakwizilwanyana zasekhaya, musa ukugungxula amayeza kwindlu yangasese okanye uwagalele kumsele wokuhambisa amanzi ngaphandle kokuba uyalelwe njalo. Yilahle ngokufanelekileyo le mveliso xa iphelelwe lixesha okanye ingasafuneki. Nxibelelana nekhemesti yakho okanye inkampani yakho yokulahla inkunkuma.
Iphepha elichazayo ukuba awusenanto oyifunayo: Abaphathiswa benze konke okusemandleni ukuqinisekisa ukuba yonke ingcaciso ichanekile, igqityiwe kwaye ihlaziyiwe. Nangona kunjalo, eli nqaku akufuneki lisetyenziswe endaweni yolwazi kunye namava oqeqeshiweyo okhathalelo lwempilo. Kuya kufuneka usoloko uqhagamshelana nogqirha wakho okanye nolunye uqeqesho kwezempilo ngaphambi kokuba uthathe naliphi na iyeza.
Ulwazi lweziyobisi oluqulethwe apha luyakwazi ukutshintsha kwaye alujoliswanga ekusetyenzisweni konke okunokwenzeka, imiyalelo, izilumkiso, izilumkiso, ukuhlangana kweziyobisi, ukungahambelani komzimba, okanye iziphumo ezibi. Ukungabikho kwezilumkiso okanye olunye ulwazi ngesiyobisi esithile akubonisi ukuba indibaniselwano yeziyobisi ikhuselekile, iyasebenza, okanye ilungele zonke izigulana okanye zonke izinto ezizisebenzisayo.
IZALATHISO
- Yonke imihla. IASID YOKUFUNDA; IBIOTIN; CHOLECALCIFEROL; ICYANOCOBALAMIN; I-DEXPANTHENOL; IFOLIC ACID; NIACINAMIDE; IPYRIDOXINE; RIBOFLAVIN; UTIAMINE; TOCOPHEROL ACETATE; IVITAMIN A; VITAMIN K: I-DailyMed ibonelela ngolwazi oluthembekileyo malunga neziyobisi ezithengisiweyo eMelika. I-DailyMed ngumboneleli osemthethweni wolwazi lweelebhile ze-FDA (ukufakwa kwephakheji) .. https://dailymed.nlm.nih.gov/dailyme… (kufumaneka ngoSeptemba 17, 2018).
- Yonke imihla. I-DICLOFENAC EPOLAMINE: I-DailyMed ibonelela ngolwazi oluthembekileyo malunga neziyobisi ezithengisiweyo eMelika. I-DailyMed ngumboneleli osemthethweni wolwazi lweelebhile ze-FDA (ukufakwa kwephakheji) .. https://dailymed.nlm.nih.gov/dailyme… (kufumaneka ngoSeptemba 17, 2018).
- I-PubChem. diclofenac. https://pubchem.ncbi.nlm.nih.gov/com… (kufumaneka ngoSeptemba 17, 2018).
- I-PubChem. thiamine. https://pubchem.ncbi.nlm.nih.gov/com… (kufumaneka ngoSeptemba 17, 2018).
- I-PubChem. ipyydoxine. https://pubchem.ncbi.nlm.nih.gov/com… (kufumaneka ngoSeptemba 17, 2018)
Iziqulatho
- Isenzo amayeza
- Pharmacokinetics
- Kutheni le nto iTribedoce) imiselwe?
- Isisombululo kunye nolawulo
- Izizwe ezilishumi elinambini iziphumo ebezingalindelekanga, iimpendulo ezigwenxa
- Tribedoce) Izimo
- Tribedoce) ngexesha lokukhulelwa kunye nokuncancisa
- Imiyalelo ekhethekileyo
- Intsapho intsebenziswano elinambini
- I-Tribedoce amayeza asebenzayo aqukethe igama lebrendi kunye neziyobisi eziqhelekileyo ezinxulumene:
- Iinkampani zoxubo-ntloko ezilishumi elinambini:
- Imibuzo esoloko ibuzwa
- Ukugqithisa
- Amanqaku
- Ukugcina
- Amagama eNkuthazo anokutshintsha ubomi bakho
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